Performance Supplement Update
Monday, October 16th, 2006Killer New Fat Loss Compounds
By Vince Andrich

Wouldn’t it be nice if science had THE PILL that made bodyfat merely melt away? Sounds great right? Don’t misunderstand me, I am a big fan of science, but I hope the magic pill NEVER comes. The reason is, if hard work, dedication and persistence are taken out of the equation, all the benefits we have as bodybuilding artists will amount to ZERO. I don’t know about you, but I like the fact that what I do with my hobby of diet and exercise makes me different than the €˜normal’ people on the street. So, I am not a fan of getting a FREE ride, but I do appreciate it when science brings us new compounds that will help us build leaner more attractive bodies.

Accelerating Your Fat Loss €˜Investment’
Even if the fat loss miracle PILL never arrives, science is making great strides in uncovering the variables associated with fat gain and loss. One of my good friends Peter Miller at Integrity Nutraceuticals turned me on to two such ingredients that look like KILLER fat loss compounds. Believe me when I tell you, Pete Miller has the science down COLD, so I think both of these compounds are definitely worth looking at (product developers go here www.integritynut.com).
“An analysis of the history of technology shows that technological change is exponential, contrary to the common-sense “intuitive linear view. So we won’t experience 100 years of progress in the 21st century€”it will be more like 20,000 years of progress…at today’s rate … Artificial Intelligence Expert Ray Kurzweil

Razberi-K …Radical Fat Burning Swiss Army Knife
The first interesting compound is called Razberi-K, also known as 4-(4-hydroxyphenyl) butan-2-one, which is a ketone unique to red raspberry. Raspberries contain many bioactive constituents beneficial for health. One particular constituent, 4-(4-hydroxyphenyl) butan-2-one appears to have the potential to decrease body fat. In a recent study, mice were fed a high fat diet to induce obesity while treated groups were also fed an additional 1 or 2% raspberry ketone. The treated groups gained less body fat than the control groups.
How does Razberi-K work?
In laymen terms, Razberi-K appears to have at least two beneficial effects for losing bodyfat namely, decreasing absorption of dietary fat and increasing norepinephrine-induced lipolysis (see http://blog.bodybuilding.com/vince_andrich/2006/10/12/neuro-chemical-diet-warfare/). Importantly, research suggests that in the reduction of absorption of dietary fat, the inhibition of trioleoylglycerol hydrolysis plays a major role. Further research advocates that enhancing lipolysis may augment glycerol release, increasing the translocation of hormone sensitive lipase (HSL) in fat cells, and increasing brown adipose tissue, known to increases thermogensis and oxidation of body fat.
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Application and Serving Size
Razberi-K is appropriate in a product for weight management. It can be administered in a capsule, tablet, powder or liquid. The recommended serving is 100 mgs twice daily.
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Look for products with the Integrity Nutraceuticals Trademarks, to be sure you’re getting the real deal!

iFAS50…Putting the Brakes on Fat Storage
Another very interesting fat loss compound is called iFAS50. According to the R & D staff at Integrity Nutraceuticals, this novel ingredient is comprised of three potent Fatty Acid Synthase (FAS) inhibitors: Green Tea, Tuber Fleeceflower and Parasitic Loranthus. Processed uniquely, the herbs in iFAS50 are blended and then extracted together. This method promotes synergy and provides a consistent and even distribution of the herbs. Research suggests that Green Tea, Tuber Fleeceflower and Parasitic Loranthus are among the most potent inhibitors of FAS.
What the Science Says about iFAS50
As you might already know, Fatty Acid Synthase is a multienzyme process resulting in the synthesis of fatty acids. Regulators of FAS are insulin and glucose; hence by prolonged consumption of high-carbohydrate or fat-free diets, FAS synthesis increases. Fatty acids once produced are esterified and stored in fat cells as an oily substance called triacylglycerol. The process of FAS is mediated by the enzyme acetyl-CoA caboxylase (ACC). Glucagon, an important hormone produced by the alpha cells of the Islets of Langerhans, is known to interfere with ACC thus inhibiting FAS.
The bottom line is that when FAS is inhibited, the body’s ability to store fat is greatly reduced, making iFAS50 an excellent fat loss tool. In addition, inhibiting FAS also exerts numerous indirect properties particularly on hypothalamic neurons. FAS inhibition results in a significant reduction of feeding behavior according to studies. The last benefit is extremely interesting to me since I believe the next generation of fat loss products MUST take into consideration feeding behavior (see my blog, (see http://blog.bodybuilding.com/vince_andrich/2006/10/12/neuro-chemical-diet-warfare/).
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Application and Serving Size
iFAS503 is appropriate in a product for weight management. It can be administered in a capsule, tablet, powder or liquid. A serving of 250 mgs twice daily is suggested.
Again, look for products with the Integrity Nutraceuticals Trademarks; to be sure you’re getting the real deal!

You can reach Integrity Nutraceuticals direct by calling 941.342.0007 or via email at: sales@integritynut.com






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