Whey Protein Hydrolysate Vs Whey Protein Isolate, Insulinogenic Responses
Research has repeatedly shown that whey protein hydrolysate(WPH) increases blood plasma concentrations of amino-acids, both faster and to a greater extent than regular intact whey. But, we also know, that WPH has a different impact on hormone levels such as insulin.
A recent study measuring the blood plasma insulin response between a WHP, that was 30% hydrolyzed was compared to a whey protein isolate(WPH). Sixteen healthy males ingested 45g of either WPH or WPI. What was found was the WPH brought about a 28% greater plasma insulin response than the WPI and the area under curve was 43% greater with the WPH compared to the WPI.
Research has shown only a small amount of insulin is needed to prime protein synthesis and increasing insulin above 10-15U/ml does not increase protein synthesis or decrease protein degradation to any further extent. Another recently completed study Koopmen R, Beelen M,. et al showed hydrolyzed protein(PeptoPro) increased plasma insulin levels to 16.5 U/ml and showed that adding carbohydrates to it had no additional impact on muscle protein synthesis.
This makes sense, as it through spiking insulin that carbohydrates exert their anabolic and anticatabolic effects. But the hydrolyzed protein without carbohydrates, easily increased the maximum amount of insulin shown needed to prime protein synthesis.
Based off these two studies finding and others, it appears, that extensively hydrolyzed whey, in these two studies cases, hydrolyzed 30% or greater can be used post-workout, without carbohydrate to maximally stimulate net muscle protein synthesis.
Power O, Hallihan A, Jakeman P.
Amino Acids. 2008 Aug 5. [Epub ahead of print]
Human insulinotropic response to oral ingestion of native and hydrolysed whey protein.
Written by:ATHLETIC EDGE NUTRITION
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November 6, 2009 - 7:42 am MDT at 7:42 am
what about the post workout cortisol reducing anti-catabolic effect carbohydrates would provide ?