HMB logg
What is HMB and what are the uses for it?
A review in Nutrition & Metabolism provides an in depth and objective analysis of HMB research. <sup class="reference" id="cite_ref-3">[4] The same study lists as HMBs proposed mechanisms of action the following:
- Increased sarcolemmal integrity via conversion to HMG-CoA
- Enhanced protein synthesis via the mTOR pathway
- Depression of protein degradation through inhibition of the ubiquitin pathway
Three grams of HMB per day may help muscles combat protein breakdown, assist in muscle repair and support increased endurance. Studies suggest its benefits may be greater for the untrained. Also, well-controlled scientific studies have found increases in muscle mass and decreases in body fat in 70 year old men. It has helped patients with chronic obstructive pulmonary disease in hospital intensive care units, muscle wasting associated with HIV or AIDS and with cancer, and trauma victims with severe injuries.<sup title=”This claim needs references to reliable sources from September 2007″ class=”noprint Template-Fact” style=”white-space: nowrap”>[citation needed]
The human body produces about 0.2-0.4 grams per day. Standard doses in research studies have been 1.5 to 3.0 grams per day, usually divided into two doses.
I have added this supplement into my nutrition and will weekly update you on my progress–I take the doses 3x a day, always with meal having protein.
As always!
Eyes on the prize!
November 2, 2009 at 7:48 am
I look forward to these updates. I have looked at this supplement, but I don’t know what I want to do about it yet. It is pretty pricey, but if it works, I could do a cycle before the new year with the hope that I hit my goal.